M. Pruschy: search on Z-Library

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1

Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin

Yandong Shi, Emanuela Felley-Bosco, Thomas M Marti, Katrin Orlowski, Martin Pruschy, Rolf A Stahel

Journal:

Year:

2012

Language:

english

File:

PDF, 843 KB

english, 2012

2

Combined Treatment Strategies for Microtubule Stabilizing Agent-Resistant Tumors

Broggini-Tenzer, A., Sharma, A., Nytko, K. J., Bender, S., Vuong, V., Orlowski, K., Hug, D., O'Reilly, T., Pruschy, M.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2015

Language:

english

File:

PDF, 20.76 MB

english, 2015

3

The novel microtubule targeting agent BAL101553 in combination with radiotherapy in treatment-refractory tumor models

Sharma, Ashish, Broggini-Tenzer, Angela, Vuong, Van, Messikommer, Alessandra, Nytko, Katarzyna J., Guckenberger, Matthias, Bachmann, Felix, Lane, Heidi A., Pruschy, Martin

Journal:

Radiotherapy and Oncology

Year:

2017

Language:

english

File:

PDF, 1.45 MB

english, 2017

4

Novel radiosensitizers for locally advanced epithelial tumors: inhibition of the PI3K/Akt survival pathway in tumor cells and in tumor-associated endothelial cells as a novel treatment strategy?

Oliver Riesterer, Angela Tenzer, Daniel Zingg, Barbara Hofstetter, Van Vuong, Martin Pruschy, Stephan Bodis

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2004

Language:

english

File:

PDF, 327 KB

english, 2004

5

Apoptosis-modulating agents in combination with radiotherapy—current status and outlook

Claus Belka, Verena Jendrossek, Martin Pruschy, Stefan Vink, Marcel Verheij, Wilfried Budach

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2004

Language:

english

File:

PDF, 509 KB

english, 2004

6

G2/M cell cycle checkpoint is functional in cervical cancer patients after initiation of external beam radiotherapy

Ferdinando Cerciello, Barbara Hofstetter, Sherweif Abdel Fatah, Mohamed Zaghloul, Bernhard Odermatt, Stephan Bodis, Zsuzsanna Varga, Martin Pruschy, Ilja F. Ciernik

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2005

Language:

english

File:

PDF, 427 KB

english, 2005

7

Mechanistic studies of a signaling pathway activated by the organic dimerizer FK1012

Martin N. Pruschy, David M. Spencer, Tarun M. Kapoor, Hiroshi Miyake, Gerald R. Crabtree, Stuart L. Schreiber

Journal:

Chemistry & Biology

Year:

1994

Language:

english

File:

PDF, 1.28 MB

english, 1994

8

Differential DNA Repair Mechanisms in Response to Proton and Photon Irradiation

N. Frenzel, E. Hug, A. Lomax, A. Staab, A. Sartori, M. Pruschy

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 56 KB

english, 2009

9

Role of the Microenvironment and Tumor Hypoxia for Radiosensitization by Patupilone

M.N. Pruschy, K. Orlowski, C. Rohrer Bley

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

10

Impact of Genomic Methylation on Radiation Sensitivity of Colorectal Carcinoma

Barbara Hofstetter, Andrzej Niemierko, Christian Forrer, Jean Benhattar, Veronica Albertini, Martn Pruschy, Fred T. Bosman, Carlo V. Catapano, I. Frank Ciernik

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 852 KB

english, 2010

11

Key targets for the execution of radiation-induced tumor cell apoptosis: the role of p53 and caspases

Martin Pruschy, Sonia Rocha, Kathrin Zaugg, Angela Tenzer, Cyrill Hess, David E Fisher, Christoph Glanzmann, Stephan Bodis

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 294 KB

english, 2001

12

55 S-phase checkpoint elements of the E2F-1 family increase radiosensitivity in fibrosarcoma cells lacking p53

Bodis Stephan, Pruschy Martin, Wirbelauer Christiane, Glanzmann Christoph, Krek Wilhelm

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

13

The PKC-inhibitor N-Benzoylstaurosporine sensitizes ceramide-resistant and p53-deficient fibrosarcomas to ionizing radiation in vivo

Pruschy Martin, Resch Hildegard, Fabbro Doriano, Shi Yu-Quan, Glanzmann Christoph, Bodis Stephan

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1998

Language:

english

File:

PDF, 110 KB

english, 1998

14

c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients

André O von Bueren, Christoph Oehler, Tarek Shalaby, Katja von Hoff, Martin Pruschy, Burkhardt Seifert, Nicolas U Gerber, Monika Warmuth-Metz, Duncan Stearns, Charles G Eberhart, Rolf D Kortmann, Stef

Journal:

Year:

2011

Language:

english

File:

PDF, 447 KB

english, 2011

15

MVP and vaults: a role in the radiation response

Pedro C Lara, Martin Pruschy, Martina Zimmermann, Luis Alberto Henríquez-Hernández

Journal:

Radiation Oncology

Year:

2011

Language:

english

File:

PDF, 266 KB

english, 2011

16

Ionizing radiation and inhibition of angiogenesis in a spontaneous mammary carcinoma and in a syngenic heterotopic allograft tumor model: a comparative study

Oliver Riesterer, Christoph Oehler-Jänne, Wolfram Jochum, Angela Broggini-Tenzer, Van Vuong, Martin Pruschy

Journal:

Radiation Oncology

Year:

2011

Language:

english

File:

PDF, 687 KB

english, 2011

17

Profiling treatment-specific post-translational modifications in a complex proteome with subtractive substrate phage display

Angela Tenzer, Barbara Hofstetter, Christelle Sauser, Stephan Bodis, August P. Schubiger, Christophe Bonny, Martin Pruschy

Journal:

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

18

Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation

Angela Broggini-Tenzer, Andreas Hollenstein, Zbigniew Pianowski, Andrea Wampfler, Polina Furmanova, Nicolas Winssinger, Martin Pruschy

Journal:

Year:

2010

Language:

english

File:

PDF, 334 KB

english, 2010

19

Substrate screening identifies a novel target sequence for the proteasomal activity regulated by ionizing radiation

Angela Broggini-Tenzer, Andreas Hollenstein, Zbigniew Pianowski, Andrea Wampfler, Polina Furmanova, Nicolas Winssinger, Martin Pruschy

Journal:

PROTEOMICS - Clinical Applications

Year:

2010

Language:

english

File:

PDF, 194 KB

english, 2010

20

Grundlagen einer innovativen interdisziplinären Tumortherapie

D. Meyer, H. Einsele, M.N. Pruschy, A.M. Waaga-Gasser, F. Weissinger

Journal:

Year:

2007

Language:

german

File:

PDF, 401 KB

german, 2007

21

Neue Konzepte und Substanzen zur Radiosensibilisierung

Journal:

Year:

2007

Language:

german

File:

PDF, 845 KB

german, 2007

22

Recombinant mistletoe lectin induces p53-independent apoptosis in tumour cells and cooperates with ionising radiation

Hostanska, K, Vuong, V, Rocha, S, Soengas, M S, Glanzmann, C, Saller, R, Bodis, S, Pruschy, M

Journal:

British Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

23

Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells

Pruschy, M, Resch, H, Shi, Y-Q, Aalame, N, Glanzmann, C, Bodis, S

Journal:

British Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

24

Overexpression of Bcl-2 enhances sensitivity of L929 cells to a lipophilic cationic photosensitiser

Klein, S D, Walt, H, Rocha, S, Ghafourifar, P, Pruschy, M, Winterhalter, K H, Richter, C

Journal:

Cell Death & Differentiation

Year:

2001

Language:

english

File:

PDF, 82 KB

english, 2001

25

HSV-1 amplicon-mediated post-transcriptional inhibition of Rad51 sensitizes human glioma cells to ionizing radiation

Saydam, O, Saydam, N, Glauser, D L, Pruschy, M, Dinh-Van, V, Hilbe, M, Jacobs, A H, Ackermann, M, Fraefel, C

Journal:

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

26

Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells

Riesterer, Oliver, Zingg, Daniel, Hummerjohann, Jörg, Bodis, Stephan, Pruschy, Martin

Journal:

Year:

2004

Language:

english

File:

PDF, 420 KB

english, 2004

27

Effect of VEGF receptor inhibitor PTK787/ZK222548 combined with ionizing radiation on endothelial cells and tumour growth

Hess, C, Vuong, V, Hegyi, I, Riesterer, O, Wood, J, Fabbro, D, Glanzmann, C, Bodis, S, Pruschy, M

Journal:

British Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 137 KB

english, 2001

28

Lateral clustering of the adhesive ectodomain: a fundamental determinant of cadherin function

Alpha S. Yap, William M. Brieher, Martin Pruschy, Barry M. Gumbiner

Journal:

Current Biology

Year:

1997

Language:

english

File:

PDF, 167 KB

english, 1997

29

Induction of plasminogen activator inhibitor type-1 (PAI-1) by hypoxia and irradiation in human head and neck carcinoma cell lines

Daniela Schilling, Christine Bayer, Anneke Geurts-Moespot, Fred CGJ Sweep, Martin Pruschy, Karin Mengele, Lisa D Sprague, Michael Molls

Journal:

Year:

2007

Language:

english

File:

PDF, 362 KB

english, 2007

30

RNA interference-mediated c-MYC inhibition prevents cell growth and decreases sensitivity to radio- and chemotherapy in childhood medulloblastoma cells

André O von Bueren, Tarek Shalaby, Christoph Oehler-Jänne, Lucia Arnold, Duncan Stearns, Charles G Eberhart, Alexandre Arcaro, Martin Pruschy, Michael A Grotzer

Journal:

Year:

2009

Language:

english

File:

PDF, 492 KB

english, 2009

31

The Proto-oncogene c-fos Mediates Apoptosis in Murine T-Lymphocytes Induced by Ionizing Radiation and Dexamethasone

Martin Pruschy, Yu-Quan Shi, Nigel E.A. Crompton, Joachim Steinbach, Adriano Aguzzi, Christoph Glanzmann, Stephan Bodis

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 351 KB

english, 1997

32

Recombinant Human Renin Produced in Different Expression Systems: Biochemical Properties and 3D Structure

Salima Mathews, Heinz Döbeli, Martin Pruschy, Ramon Bosser, Allan D'Arcy, Christian Oefner, Martin Zulauf, Reiner Gentz, Volker Breu, Hugues Matile, Jürgen Schlaeger, Walter Fischli

Journal:

Protein Expression and Purification

Year:

1996

Language:

english

File:

PDF, 197 KB

english, 1996

33

Temperature sensitivity of phospho-Ser473-PKB/AKT

Christoph Oehler-Jänne, André O. von Bueren, Van Vuong, Andreas Hollenstein, Michael A. Grotzer, Martin Pruschy

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 557 KB

english, 2008

34

Interferon-γ mediated up-regulation of caspase-8 sensitises medulloblastoma cells to radio- and chemotherapy

N. Meister, T. Shalaby, A.O. von Bueren, P. Rivera, R. Patti, C. Oehler, M. Pruschy, M.A. Grotzer

Journal:

European Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 871 KB

english, 2007

35

81 - Effect of E2F-1 and E2F-1-mutants on the cellular survival and radiosensitivity

M. Pruschy, C. Glanzmann, C. Wirbelauer, S. Bodis, W. Krek

Journal:

European Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 251 KB

english, 1997

36

Cooperative in vivo cytotoxicity of ionizing radiation and the protein kinase C-inhibitor PKC412 in p53-deficient, radioresistant tumor cells

K. Zaugg, H. Resch, I. Hegyi, C. Glanzmann, D. Fabbro, S. Bodis, M. Pruschy

Journal:

European Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 142 KB

english, 1999

37

Tumor Recovery by Angiogenic Switch from Sprouting to Intussusceptive Angiogenesis after Treatment with PTK787/ZK222584 or Ionizing Radiation

Ruslan Hlushchuk, Oliver Riesterer, Oliver Baum, Jeanette Wood, Guenther Gruber, Martin Pruschy, Valentin Djonov

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 3.04 MB

english, 2008

38

Metabolism of tumors under treatment: Mapping of metabolites with quantitative bioluminescence

Angela Broggini-Tenzer, Van Vuong, Martin Pruschy

Journal:

Radiotherapy and Oncology

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

39

75 p53 signaling and novel mechanisms for targeted radiosensitizers

S. Bodis, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2003

Language:

english

File:

PDF, 170 KB

english, 2003

40

479 Inhibition of angiogenesis and ionizing radiation: treatment-dependent influence on the tumor microenvironment

O. Riesterer, V. Djonov, M. Honer, S. Ametamey, S. Bodis, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2003

Language:

english

File:

PDF, 162 KB

english, 2003

41

88 Substrate phage display: screening-approach for radiation-induced posttrasnlational peptide modifications in a complex proteome

A. Broggini-Tenzer, B. Hofstetter, C. Sauser, S. Bodis, P. Schubiger, C. Bonny, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 297 KB

english, 2004

42

537 Multidrug-resistant tumors treated with Epothilone B in combination with clinically relevant doses of ionizing radiation

B. Hofstetter, V. Vuong, A. Broggini-Tenzer, M. Wartmann, D. Fabbro, S. Bodis, G. Folkers, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 273 KB

english, 2004

43

647 Modulation of tumor hypoxia in response to treatment with ionizing radiation and the VEGFR inhibitor PTK787/ZK222584

O. Riesterer, M. Honer, C. Oehler, V. Djonov, S. Ametamey, S. Bodis, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 137 KB

english, 2004

44

653 Optimization of novel antiangiogenic treatment modalities in combination with ionizing radiation

O. Riesterer, C. Oehler, D. Zingg, V. Vuong, A. Broggini-Tenzer, D. Fabbro, S. Bodis, M. Pruschy

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 138 KB

english, 2004

45

Microtubule stabilising agents and ionising radiation: Multiple exploitable mechanisms for combined treatment

Carla Rohrer Bley, Polina Furmanova, Katrin Orlowski, Nicole Grosse, Angela Broggini-Tenzer, Paul M.J. McSheehy, Martin Pruschy

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 688 KB

english, 2013

46

Bioluminescence imaging for in vivo monitoring of local recurrence mesothelioma model

Shi, Yandong, Hollenstein, Andreas, Felley-Bosco, Emanuela, Fraefel, Cornel, Ackermann, Matthias, Soltermann, Alex, Weder, Walter, Stahel, Rolf, Pruschy, Martin, Opitz, Isabelle

Journal:

Year:

2011

Language:

english

File:

PDF, 394 KB

english, 2011

47

Regulation of VEGF-expression by patupilone and ionizing radiation in lung adenocarcinoma cells

Rohrer Bley, Carla, Orlowski, Katrin, Furmanova, Polina, McSheehy, Paul M.J., Pruschy, Martin

Journal:

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

48

148 Complementary in vitro and in vivo study of the promising combined treatment modality of ionizing radiation and patupilone (EP0906, epothilone B)

B. Hofstetter, Ch. Oehler, V. Vuong, A. Broggini-Tenzer, I.F. Ciernik, M. Wergin, M. Wartmann, S. Rüetz, P. McSheehy, M. Pruschy

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

49

180 The nuclear pore complex is a target in the cellular stress response to ionizing radiation

A. Broggini-Tenzer, A. Hollenstein, B. Hofstetter, D. Dickinson, M. Pruschy

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

50

22 Optimization of the treatment modality combining ionizing radiation with inhibitors of angiogenesis

M. Pruschy, C. Oehler, V. Vuong, A. Broggini-Tenzer, W. Jochum, M. Honer, O. Riesterer

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 134 KB

english, 2006

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